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  • br Boffa DJ Allen MS

    2020-03-17


    52. MF498 Boffa DJ, Allen MS, Grab JD, Gaissert HA, Harpole DH, Wright CD. Data from the Society of Thoracic Surgeons general thoracic surgery database: the surgical management of primary lung tumors. J Thorac Cardiovasc Surg. 2008;135: 247-54.
    53. Stokes WA, Bronsert MR, Meguid RA, Blum MG, Jones BL, Koshy M, et al. Post-treatment mortality after surgery and stereotactic body radiotherapy for early-stage non-small-cell lung cancer. J Clin Oncol. 2018;36:642-51.
    56. Rosenbaum P, Rubin D. Reducing bias in observational studies using subclassification on the propensity score. J Am Stat Assoc. 1984;79:516-24.
    57. Lunt M. Selecting an appropriate caliper can be essential for achieving good balance with propensity score matching. Am J Epidemiol. 2014;179: 226-35.
    Key Words: stereotactic body MF498 therapy, surgery, non–small cell lung cancer, survival, meta-analysis 
    THOR
    The Journal of Thoracic and Cardiovascular Surgery c Volume 157, Number 1 373
    THOR  Thoracic: Lung Cancer: Review Cao et al
    Identification
    Records identified through
    Additional records identified
    database searching
    through other sources
    Screening
    Records after duplicates
    removed
    Records screened
    Records excluded as case
    reports, comments, letters,
    reviews, or irrelevant papers
    Eligibility
    Full-text articles assessed
    Articles excluded after
    for eligibility
    applying selection criteria
    Included
    Studies included in
    Removal of overlapping or
    systematic review
    incomplete reports
    Studies included for
    quantitative meta-analysis
    FIGURE E1. PRISMA flow chart summarizing the literature search strategy in the systematic review of SBRT versus surgical resection for patients with early-stage NSCLC.
    Odds Ratio Odds Ratio
    Study or Subgroup log [Odds Ratio] SE Weight IV, Random, 95% CI IV, Random, 95% CI
    Favours [SBRT]
    Favours [surgery]
    FIGURE E2. Forest plot of the OR of overall survival in unmatched patients after SBRT versus lobectomy in patients with early-stage NSCLC. The estimate of the OR of each study corresponds to the middle of the squares, and the horizontal line shows the 95% CI. On each line, the numbers of events as a fraction of the total number randomized are shown for both treatment groups. For each subgroup, the sum of the statistics, along with the summary OR, is represented by the middle of the solid diamonds. A test of heterogeneity between the trials within a subgroup is given below the summary statistics. SE, Standard error; CI, confidence interval; SBRT, stereotactic body radiation therapy.
    373.e1 The Journal of Thoracic and Cardiovascular Surgery c January 2019
    Cao et al Thoracic: Lung Cancer: Review
    Odds Ratio
    Odds Ratio
    Study or Subgroup log [Odds Ratio] SE Weight IV, Random, 95% CI IV, Random, 95% CI
    Favours [SBRT]
    Favours [surgery]
    FIGURE E3. Forest plot of the OR of overall survival in matched patients after SBRT versus lobectomy in patients with early-stage NSCLC. The estimate of the OR of each study corresponds to the middle of the squares, and the horizontal line shows the 95%CI. On each line, the numbers of events as a fraction of the total number randomized are shown for both treatment groups. For each subgroup, the sum of the statistics, along with the summary OR, is represented by the middle of the solid diamonds. A test of heterogeneity between the trials within a subgroup is given below the summary statistics. SE, Standard error; CI, confidence interval; SBRT, stereotactic body radiation therapy. 
    THOR